转化生物信息学及其应用（英文版）_魏冬青马亦龙曹志成徐沁周丰丰_9787313180957

　　《转化生物信息学及其应用（英文版）》系“转化医学出版工程：技术系列”之一，邀请了国内外生物、医学、信息学方面的专家学者介绍其*前沿的研究成果，从不同角度展现其研究过程中应用转化医学信息学相关方法或工具的实例，主要包括以下儿个方面：（1）组学数据分析协助精准医疗；（2）通过计算生物学方法，探索成药机制，指导药物研发；（3）计算机辅助药物发现，通过定向设计与虚拟筛选更为高效快速地使众多先导化合物向临床药物转化；（4）利用大数据，通过生物统计学、生物信息学和系统生物学方法研究复杂疾病；（5）生物成像及其他信息学技术在转化医学中的应用。
　　《转化生物信息学及其应用（英文版）》实用性强，可极大地开拓基础和临床医学工作人员的思路。

　　Over the years，a chasm between biomedical researchers and the patients who may benefit from their discoveries has been opened. On one hand， millions of patients with diseases such as cancer are anxiously waiting for new remedies to save their lives. On the other hand， many exciting basic science discoveries do not have opportunities to find practical applications. Recently emerging translational medicine aims to tie basic research to clinical results and optimize both patient care and preventive measures.
　　Translational medicine converts promising laboratory discoveries into clinical applications and elucidates clinical questions with the use of bench work， aiming to facilitate prediction， prevention， diagnosis， and treatment of diseases. With the ultimate goal to develop more effective preventive/therapeutic approaches and improve clinical outcomes and health levels， translational medicine is therefore a people （patients and the general population as a whole）-oriented medical practice.
　　The past three decades have witnessed tremendous advances in China in the development of living conditions， food and nutrition， and the health care system. However， while the economy grows and society rapidly transforms， the health care system faces multiple problems. China bears a complex disease spectrum： On one hand， communicable diseases frequently seen in developing countries remain a heavy burden; on the other hand， chronic diseases commonly found in developed countries are also the leading causes of death and disability in China. The situation shows that the health care system in China is facing great challenges， and a state effort is needed to meet these challenges. Therefore China is deepening its reform to improve its people's welfare. The development of translational medicine will accelerate disease control and finding solutions for health problems.
　　Translational medicine is a multidisciplinary program that integrates research from the medical sciences， basic sciences， and social sciences， with the aim of optimizing patient care and preventive measures that may extend beyond health care services. Therefore， close collaboration in an international scale among all the parties is essential to the development of translational medicine.
　　To enhance the aforementioned international collaboration as well as to provide a forum for communication and cross-fertilization among basic， translational， and clinical research practit.ioners， we launch the book series "Translational Medicine Research". It features original and observational investigations in the broad fields of laboratory， clinical， and public health research， aiming to provide practical up- to-date information in significant research from all subspecialties of medicine and to broaden the readers' vision and horizon from bench to bed and bed to bench.
　　In close collaboration with National Infrastructures for Translational Medicine （Shanghai）， the book series "Translational Medicine Research" serves as a state- of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of translational medicine. As the Editor- in-Chief， I welcome all the researchers in related areas to report the latest bench- to-bedside researches in this series， so that the series can promote human health by accelerating the knowledge dissemination in global community.

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